This is an important question. IVF cycles are monitored with serial measurements of estrogen , LH ,and Progesterone. At times , towards the last day of stimulation we observe a slight rise of progesterone. some have questioned whether this progesterone level increase ( slight increase not majour ovulation increases of 2 or 3) reduces the chance of pregnancy.
The short answer to this question is "the best available evidence does not support an association between progesterone elevation on the day of hCG administration and the probability of clinical pregnancy in women undergoing ovarian stimulation with GnRH analogues and gonadotrophins for IVF".
This is based on a large meta analysis that you can find here
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